two. Histamine Receptor Antagonism: Some sedatives, including antihistamines, exert their sedative effects by blocking histamine receptors from the brain, specially H1 receptors. Histamine plays a task in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Don’t mix sedatives with each other or with other remedies which https://sedatives-drugs33086.blogoscience.com/39287041/safe-usage-of-sedatives-best-practices-key-considerations